Enhanced Parkin-mediated mitophagy mitigates adverse left ventricular remodelling after myocardial infarction: role of PR-364

doi:https://doi.org/10.1093/eurheartj/ehae782

Open AccessArticle10.1093/eurheartj/ehae782

Enhanced Parkin-mediated mitophagy mitigates adverse left ventricular remodelling after myocardial infarction: role of PR-364

Lizhuo Ai,Juliana de Freitas Germano,Chengqun Huang,Marianne Aniag,Savannah Sawaged,Jon Sin+12 more-2024-11-27-European Heart Journal

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TL;DRAbstract

This study demonstrates the therapeutic potential of targeting Parkin-mediated mitophagy using PR-364 to protect surviving cardiac tissue post-MI from progression to HF.

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This study demonstrates the therapeutic potential of targeting Parkin-mediated mitophagy using PR-364 to protect surviving cardiac tissue post-MI from progression to HF.

Keywords

Mitophagy Parkin Medicine Mitochondrion Autophagy Mitochondrial biogenesis Cell biology Myocardial infarction

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