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Article10.1002/ajmg.1320580412

Maternal origin of extra haploid set of chromosomes in third trimester triploid fetuses

E. Dietzsch,Michèle Ramsay,Arnold L. Christianson,B Henderson,Thomy de Ravel-1995-09-25-American Journal of Medical Genetics
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TL;DRAbstract

Twenty-six highly polymorphic markers were used to determine the origin of the extra haploid chromosome set in 6 triploid fetuses of type II phenotype. All had reached the third trimester of pregnancy. The extra set was maternal in origin in all cases, supporting previous research indicating longer in utero survival of maternally-derived triploid fetuses. These findings provide evidence for an instance of genomic imprinting in humans.

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Twenty-six highly polymorphic markers were used to determine the origin of the extra haploid chromosome set in 6 triploid fetuses of type II phenotype. All had reached the third trimester of pregnancy. The extra set was maternal in origin in all cases, supporting previous research indicating longer in utero survival of maternally-derived triploid fetuses. These findings provide evidence for an instance of genomic imprinting in humans.

Keywords

PloidyBiologyFetusGeneticsAndrologyPregnancyMedicineGene

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