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感染猪囊尾蚴的家猪组织中不同时间IL-6、IL-8、TNF-α和sIL-2R含量变化

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To measure the levels of IL-6, IL-8, TNF-α and sIL-2 receptor (sIL-2R) in tissues of pigs infected with cysticercus cellulosae of Taenia sodium in order to explore the immune mechanism of this infection from standpoint of cytokines and their receptors, four pigs of 20 days old were infected with a dose of 80 000 eggs of T. sodium and the levels of IL-6, IL-8, TNF-α and sIL-2R in the infected tissues of pigs were measured on 40th, 60th, 80th and 120th day after infection by ELISA assay. It was found that the levels of these cytokines and receptor in liver, skeleton muscle, myocardium, muscles of tongue and brain during the experimental periods in the control group of animal were quite stable, while in the experimental group, those in the liver tissues were obviously different in comparison with those of the the control group 40 days after infection (P<0.01); little difference existed in 80th day, (P<0.05), and no living cysticercus cellulosae could be detected in liver tissues in 120th

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To measure the levels of IL-6, IL-8, TNF-α and sIL-2 receptor (sIL-2R) in tissues of pigs infected with cysticercus cellulosae of Taenia sodium in order to explore the immune mechanism of this infection from standpoint of cytokines and their receptors, four pigs of 20 days old were infected with a dose of 80 000 eggs of T. sodium and the levels of IL-6, IL-8, TNF-α and sIL-2R in the infected tissues of pigs were measured on 40th, 60th, 80th and 120th day after infection by ELISA assay. It was found that the levels of these cytokines and receptor in liver, skeleton muscle, myocardium, muscles of tongue and brain during the experimental periods in the control group of animal were quite stable, while in the experimental group, those in the liver tissues were obviously different in comparison with those of the the control group 40 days after infection (P<0.01); little difference existed in 80th day, (P<0.05), and no living cysticercus cellulosae could be detected in liver tissues in 120th

Keywords

ReceptorImmune systemTumor necrosis factor alphaBiologyInternal medicineEndocrinologyMedicinePathology

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