Effect of salivaryadenectomy of the pregnant mother on testicular lactase dehydrogenase in mice

TL;DRAbstract

The large body of evidences indicate that epidermal growth factor (EGF) is synthesized, stored and secreted by the submandibular glands and also by the sublingual glands. EGF shows stimulating activity on various epidermal epithelial tissues both in vitro and in vivo. A series of observations suggest that the growth factors and in particular EGF plays an important role in the male reproductive system. The concentration of EGF in the submandibular gland and plasma of the female mice increases substantially during pregnancy. The midgestational sialoadenectomy of female mice reduces EGF level. To show the effect of salivariadenectomy of the pregnant mother, on the development and function of testis, testicular lactase dehydrogenase isoenzyme was studied biochemically and electrophoretically. LDH-X is one of the LDH isoenzymes which is unique to pachytene spermatocytes, spermatids and mature sperm. The pregnant females were salivariadenectomised (sublingualectomy, sialoadenectomy and bot

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