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Discovery of druggable biologics from alternanthera paronychiodes

Weijian Ye-2010-01-01-DR-NTU (Nanyang Technological University)
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TL;DRAbstract

Over the years, the chemical profiles of numerous herbs have been characterized, the majority of which are non-peptide compounds. This could be due to the novelty of the idea of peptides being a biologically active compound, and hence are not actively being screened for. Recently, it was found that Viola Yedoensitis (Violaceae), 紫花地丁, a Chinese medicinal herb, contains biologically active cyclotides (Wang, Colgrave et al. 2007). [1st Award]

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Over the years, the chemical profiles of numerous herbs have been characterized, the majority of which are non-peptide compounds. This could be due to the novelty of the idea of peptides being a biologically active compound, and hence are not actively being screened for. Recently, it was found that Viola Yedoensitis (Violaceae), 紫花地丁, a Chinese medicinal herb, contains biologically active cyclotides (Wang, Colgrave et al. 2007). [1st Award]

Keywords

DruggabilityBiologyComputational biologyComputer scienceGeneticsGene

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