Article10.1016/j.bmcl.2015.07.089

2,4-Diarylamino-pyrimidines as kinase inhibitors co-targeting IGF1R and EGFRL858R/T790M

Shingpan Chan,Kun Han,Rong Qu,Linjiang Tong,Yingjun Li,Zhang Zhang+8 more-2015-07-30-Bioorganic & Medicinal Chemistry Letters

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Keywords

ChemistryT790MKinaseInsulin-like growth factor 1 receptorLead compoundEGFR inhibitorsIC50Pharmacology

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