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Dietary Flavonoid Intake and Weight Change

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Background Higher flavonoid consumption may be associated with less weight gain over time through mechanisms related to energy balance, glucose metabolism, fat oxidation, and adipokine secretion. Objective To examine whether intake of specific flavonoid sub‐classes is associated with weight change over time. Methods We examined the association between change in intake of the range of flavonoid sub‐classes and change in weight in three large prospective cohorts of 124,102 men and women participating in the Health Professionals Follow‐up Study (HPFS), Nurses' Health Study (NHS), and Nurses' Health Study II (NHS II). From 1986 to 2006, these associations were examined within multiple 4‐year time intervals, adjusting for simultaneous changes in other lifestyle factors including other aspects of diet, smoking status, and physical activity. Results were combined using a fixed effects meta‐analysis. Results Increased consumption of all flavonoid sub‐classes was inversely associated with weigh

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Background Higher flavonoid consumption may be associated with less weight gain over time through mechanisms related to energy balance, glucose metabolism, fat oxidation, and adipokine secretion. Objective To examine whether intake of specific flavonoid sub‐classes is associated with weight change over time. Methods We examined the association between change in intake of the range of flavonoid sub‐classes and change in weight in three large prospective cohorts of 124,102 men and women participating in the Health Professionals Follow‐up Study (HPFS), Nurses' Health Study (NHS), and Nurses' Health Study II (NHS II). From 1986 to 2006, these associations were examined within multiple 4‐year time intervals, adjusting for simultaneous changes in other lifestyle factors including other aspects of diet, smoking status, and physical activity. Results were combined using a fixed effects meta‐analysis. Results Increased consumption of all flavonoid sub‐classes was inversely associated with weigh

Keywords

FlavonoidMedicineObesityWeight gainProspective cohort studyWeight changeDemographyWeight loss

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