User Settings
Review10.1007/978-1-60761-842-3_1

Sequencing and Genome Assembly Using Next-Generation Technologies

Niranjan Nagarajan,Mihai Pop-2010-01-01-Methods in molecular biology
53

TL;DRAbstract

Several sequencing technologies have been introduced in recent years that dramatically outperform the traditional Sanger technology in terms of throughput and cost. The data generated by these technologies are characterized by generally shorter read lengths (as low as 35 bp) and different error characteristics than Sanger data. Existing software tools for assembly and analysis of sequencing data are, therefore, ill-suited to handle the new types of data generated. This paper surveys the recent software packages aimed specifically at analyzing new generation sequencing data.

Chat with Paper

AI Agents for this Paper

Several sequencing technologies have been introduced in recent years that dramatically outperform the traditional Sanger technology in terms of throughput and cost. The data generated by these technologies are characterized by generally shorter read lengths (as low as 35 bp) and different error characteristics than Sanger data. Existing software tools for assembly and analysis of sequencing data are, therefore, ill-suited to handle the new types of data generated. This paper surveys the recent software packages aimed specifically at analyzing new generation sequencing data.

Keywords

Sanger sequencingSoftwareDNA sequencingComputer scienceThroughputData scienceData miningBiology

Chat

Click to start Chat