Isolated Gastroduodenal Crohn’s Disease

TL;DRAbstract

Introduction: Since the 1960s, evidence has shown that Crohn’s disease can affect the entire GI tract. However, isolated gastric Crohn’s disease remains a rare entity. Case Report: Herein, we present a 69-year-old woman with complaints of intermittent dysphagia to both solids and liquids, associated with severe chest pain. The patient is a former smoker without past gastrointestinal illness, who denied any family history of gastrointestinal malignancy or inflammatory bowel disease. An initial EGD showed mild erosive gastritis with benign-appearing gastric polyps and an unremarkable duodenum. Colonoscopy was also performed, demonstrating diverticulosis without signs of inflammation. Two years later, a second hospitalization for abdominal pain, early satiety, and intolerance to oral intake led to a CT scan of the abdomen, which revealed thickening and inflammatory stranding of the distal stomach. EGD demonstrated erosions and submucosal hemorrhages in the gastric antrum, as well as sever

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