When oral agents fail: optimizing insulin therapy in the older adult.

TL;DRAbstract

Basal insulin therapy, basal-bolus insulin therapy, and premixed insulin therapy are useful options for older patients inadequately controlled on one or more oral agents. Older patients who require additional postprandial control may benefit from GLP-1 analogs or DPP-4 inhibitors. Additional research is needed to determine optimal therapy in older adults treated with oral agents who require more intensive therapy.

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