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Hb-M "Hyde Park": a de novo mutation, identified by mass spectrometry and DNA analysis.

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TL;DRAbstract

This is a case of HbM Hyde-Park arising as a de novo mutation. FAB mass spectroscopic analysis is a rapid and useful analytical method for identifying aminoacid substitution.

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This is a case of HbM Hyde-Park arising as a de novo mutation. FAB mass spectroscopic analysis is a rapid and useful analytical method for identifying aminoacid substitution.

Keywords

HemoglobinAmino acid substitutionMass spectrometryMutationMethemoglobinGlobinMolecular biologyGenetics

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