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Open AccessArticle10.1007/s00213-015-4020-0

Altered performance in a rat gambling task after acute and repeated alcohol exposure

Marcia Spoelder,Heidi M. B. Lesscher,Peter Hesseling,Annemarie M. Baars,José G. Lozeman‐van t Klooster,Rob Mijnsbergen+1 more-2015-07-29-Psychopharmacology
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TL;DRAbstract

Our results show that repeated alcohol exposure alters decision making during rGT acquisition and reduces the ability to adjust choice behavior on the basis of feedback. In addition, repeated alcohol exposure unmasks its behavioral disinhibitory effects in the rGT. Impaired responsiveness to choice feedback and behavioral disinhibition may contribute to the development of AUD.

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Our results show that repeated alcohol exposure alters decision making during rGT acquisition and reduces the ability to adjust choice behavior on the basis of feedback. In addition, repeated alcohol exposure unmasks its behavioral disinhibitory effects in the rGT. Impaired responsiveness to choice feedback and behavioral disinhibition may contribute to the development of AUD.

Keywords

AlcoholNeurocognitivePunishment (psychology)PsychologyAlcohol use disorderEthanolImpulsivityAudiology

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