Effect of ligand of peroxisome proliferator-activated receptor γ on the biological characters of hepatic stellate cells
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TL;DRAbstract
By increasing expression of PPARgamma in activated HSCs, rosiglitazone, an agonist of PPARgamma, decreases alpha-SMA expression and type I collagen synthesis, inhibits cell proliferation, and induces cell apoptosis.
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By increasing expression of PPARgamma in activated HSCs, rosiglitazone, an agonist of PPARgamma, decreases alpha-SMA expression and type I collagen synthesis, inhibits cell proliferation, and induces cell apoptosis.
Keywords
RosiglitazoneHepatic stellate cellInternal medicineEndocrinologyPeroxisome proliferator-activated receptorApoptosisReceptorCell growth
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