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Application of TEDPED to analyze serum enzyme distributions in rabbits

Rex Gentry,D.E. Fields,Patricia A. Gentry-1980-01-01-OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
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TL;DRAbstract

The most common assumption regarding the natural probability distribution of data is that the data are normally distributed. However, many natural phenomena are not normally distributed. The most frequently assumed one tail distribution for continuous data is the lognormal distribution. A computer code, TEDPED, was written for testing the hypothesis that a data set is normally or lognormally distributed. The application of this code to analyze the distribution of specific serum enzymes as determined by commercial assays is illustrated. Three clinically important enzymes: alkaline phosphatase, AP; serum alanine amino transaminase, SAAT; and lactate dehydrogenase, LDH, were selected for analysis with standard commercial assays. Experimental data were determined from healthy mature New Zealand white rabbits. The AP assay was from General Diagnostic. The LDH and SAAT assays were from Fisher Scientific. The standard employed to calibrate the assays was Validate by General Diagnostic. The al

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The most common assumption regarding the natural probability distribution of data is that the data are normally distributed. However, many natural phenomena are not normally distributed. The most frequently assumed one tail distribution for continuous data is the lognormal distribution. A computer code, TEDPED, was written for testing the hypothesis that a data set is normally or lognormally distributed. The application of this code to analyze the distribution of specific serum enzymes as determined by commercial assays is illustrated. Three clinically important enzymes: alkaline phosphatase, AP; serum alanine amino transaminase, SAAT; and lactate dehydrogenase, LDH, were selected for analysis with standard commercial assays. Experimental data were determined from healthy mature New Zealand white rabbits. The AP assay was from General Diagnostic. The LDH and SAAT assays were from Fisher Scientific. The standard employed to calibrate the assays was Validate by General Diagnostic. The al

Keywords

Log-normal distributionDistribution (mathematics)Lactate dehydrogenaseNormal distributionProbability distributionChemistryEnzymeMathematics

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