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C-Alkynylation of Cyclopropanols

Rajappa Murali,Nagavaram Narsimha Rao,Jin Kun-2015-07-22-Organic Letters
58

TL;DRAbstract

Alkynylation of cyclopropanols with 1-bromo-1-alkynes has been devised for easy access to synthetically useful alk-4-yn-1-ones. This method broadens the utility of attractively functionalized cyclopropanols as a new class of homoenolate equivalent in C-C bond formation.

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Alkynylation of cyclopropanols with 1-bromo-1-alkynes has been devised for easy access to synthetically useful alk-4-yn-1-ones. This method broadens the utility of attractively functionalized cyclopropanols as a new class of homoenolate equivalent in C-C bond formation.

Keywords

ChemistryAlkynylationClass (philosophy)Combinatorial chemistryBiochemistryComputer scienceArtificial intelligenceCatalysis

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