ROBUSTNESS OF LOCAL FORCING IN INHIBITION OF REENTRY

TL;DRAbstract

It was systematically analyzed and has been shown that the low-voltage ”point” forcing is not a robust method to terminate reentrant arrhythmias. Even in homogeneous isotropic tissue simulated by a simplified ionic model it was found that success/failure of local pacing strongly depends on the type of reentry, location of the electrode, phase of stimuli during the rotation period, stimulation frequency and waveform and the size of tissue. Along with elimination of spiral waves, shift of spiral cores closer to unexcitable boundaries or no effect, the local forcing may also cause spiralwave turbulence (fibrillation) and prolong existence of an otherwise self-terminating single spiral wave (reentrant tachycardia).

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