Suppression of hypoxia-associated vascular endothelial growth factor gene expression by nitric oxide via cGMP.

Article

Suppression of hypoxia-associated vascular endothelial growth factor gene expression by nitric oxide via cGMP.

Neil Ghiso,Richard M. Rohan,Seiji Amano,R Garland,Anthony P. Adamis-1999-05-01-PubMed

71

TL;DRAbstract

These data indicate that NO decreases hypoxia-induced VEGF via a cGMP-dependent mechanism and suggest that NO may serve as an endogenous inhibitor of both hypoxia- and non- hypoxia-enhanced VEGF expression in vivo.

Chat with Paper

AI Agents for this Paper

These data indicate that NO decreases hypoxia-induced VEGF via a cGMP-dependent mechanism and suggest that NO may serve as an endogenous inhibitor of both hypoxia- and non- hypoxia-enhanced VEGF expression in vivo.

Keywords

Sodium nitroprussideNitric oxideVascular endothelial growth factorNorthern blotGene expressionMolecular biologyVascular endothelial growth factor AChemistry

Chat

Click to start Chat