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Open AccessArticle10.3904/kjim.2000.15.2.135

Acquired Hemophilia Successfully Treated With Oral Immunosuppressive Therapy

Je Jung Lee,Ik Joo Chung,Moo Rim Park,Duc Hwan Yang,Sang‐Hee Cho,Dong Wook Ryang+1 more-2000-07-31-The Korean Journal of Internal Medicine

TL;DRAbstract

Acquired hemophilia is a rare disorder associated with serious bleeding in nonhemophilic patients. We had a 40-year-old woman who was diagnosed as acquired hemophilia with a factor VIII inhibitor level of 27.5 BU/mL. She was presented with gross hematuria and severe right shoulder pain, and was successfully treated with daily oral cyclophosphamide and prednisone for 2 weeks. After the remission, the doses of prednisone and cyclophosphamide were slowly decreased and she remained in complete remission without further bleeding episodes.

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Acquired hemophilia is a rare disorder associated with serious bleeding in nonhemophilic patients. We had a 40-year-old woman who was diagnosed as acquired hemophilia with a factor VIII inhibitor level of 27.5 BU/mL. She was presented with gross hematuria and severe right shoulder pain, and was successfully treated with daily oral cyclophosphamide and prednisone for 2 weeks. After the remission, the doses of prednisone and cyclophosphamide were slowly decreased and she remained in complete remission without further bleeding episodes.

Keywords

MedicinePrednisoneCyclophosphamideComplete remissionGross hematuriaSurgeryGastroenterologyInternal medicine

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