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Noninvasive imaging of epicardial potentials: Regional constraints and clinical applications.

C.J. Penney-1999-01-01-Library and Archives Canada (Government of Canada)
2

TL;DRAbstract

Electrocardiograms (ECGs) recorded from the body surface reflect electrical activity of the heart. When a coronary artery is occluded, as occurs in balloon-inflation coronary angioplasty, blood flow is suspended, cellular oxygen supplies are depleted, and ischemia develops, altering cardiac electrical activity. The aim of this study is to locate ischemic regions of the heart by computing an image of the potentials on the heart surface from the body-surface ECGs. Rigorous mathematical methods are developed, which introduce regional constraints to overcome the ill-posed nature of this problem.

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Electrocardiograms (ECGs) recorded from the body surface reflect electrical activity of the heart. When a coronary artery is occluded, as occurs in balloon-inflation coronary angioplasty, blood flow is suspended, cellular oxygen supplies are depleted, and ischemia develops, altering cardiac electrical activity. The aim of this study is to locate ischemic regions of the heart by computing an image of the potentials on the heart surface from the body-surface ECGs. Rigorous mathematical methods are developed, which introduce regional constraints to overcome the ill-posed nature of this problem.

Keywords

CardiologyBody surfaceBlood flowAngioplastyBalloonInternal medicineMedicineMyocardial ischemia

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