TL;DRAbstract
For patients with localized carcinoid tumors, surgical resection alone is often curative. Patients with metastatic disease, on the other hand, often present a therapeutic challenge. While somatostatin analogs are highly effective in controlling symptoms of hormonal secretion, they are only rarely associated with tumor regression. Selected patients with hepatic metastases may benefit from surgical debulking, embolization, or other ablative therapies. The clinical benefit associated with the administration of systemic agents such as alpha interferon or cytotoxic chemotherapy is less clear, and the widespread use of such regimens has been limited by their relatively modest anti-tumor activity as well as concerns regarding their potential toxicity. New treatment approaches for patients with metastatic carcinoid tumors are being actively explored.
Chat with Paper
AI Agents for this Paper
For patients with localized carcinoid tumors, surgical resection alone is often curative. Patients with metastatic disease, on the other hand, often present a therapeutic challenge. While somatostatin analogs are highly effective in controlling symptoms of hormonal secretion, they are only rarely associated with tumor regression. Selected patients with hepatic metastases may benefit from surgical debulking, embolization, or other ablative therapies. The clinical benefit associated with the administration of systemic agents such as alpha interferon or cytotoxic chemotherapy is less clear, and the widespread use of such regimens has been limited by their relatively modest anti-tumor activity as well as concerns regarding their potential toxicity. New treatment approaches for patients with metastatic carcinoid tumors are being actively explored.
Keywords
Chat
Click to start Chat