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A Comparative Study between CT and Histopathologic Findings of Amyloid Goiter

Okimoto, Tomoaki,Isao Shimokawa,Hiroshi Onishi,Yoshikazu Higami,Takayoshi Ikeda,Masataka Uetani-1998-06-30-Nagasaki University's Academic Output SITE (Nagasaki University)

TL;DRAbstract

There are only a few reports describing the imaging features of amyloid goiter with adequate histopathologic correlation. We present a case of amyloid goiter, focusing the correlation between CT and autopsy specimen findings. CT showed diffuse low attenuation areas (40-50 H.U. ) which corresponded to the tissue with dense amyloid deposits. There was also focal areas of very low attenuation which contained the adipose tissue. The latter finding is relatively characteristic for amyloid goiter, because fatty infiltration is known to be frequently associated with amyloid goiter : a rare finding in other disorders.

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There are only a few reports describing the imaging features of amyloid goiter with adequate histopathologic correlation. We present a case of amyloid goiter, focusing the correlation between CT and autopsy specimen findings. CT showed diffuse low attenuation areas (40-50 H.U. ) which corresponded to the tissue with dense amyloid deposits. There was also focal areas of very low attenuation which contained the adipose tissue. The latter finding is relatively characteristic for amyloid goiter, because fatty infiltration is known to be frequently associated with amyloid goiter : a rare finding in other disorders.

Keywords

GoiterAmyloid (mycology)AmyloidosisMedicinePathologyThyroidInternal medicine

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