Perirhinal cortex and the neural basis of object memory in the rat

TL;DRAbstract

This thesis aimed to investigate the role of the perirhinal cortex in object memory in the rat. The first experiment tested the hypothesis that the perirhinal cortex is critical to memory for relationships between objects by testing postoperative learning of novel visual-visual stimulus associations following lesions of the perirhinal cortex. The hypothesis was not supported: postoperative performance was not impaired. Experiments 3.1-3.4 tested the hypothesis that perirhinal cortex is crucial to the integration of multiple features into a representation of an object using spontaneous object recognition with either reconfigured objects or multiple objects. The hypothesis was supported: perirhinal lesions caused disproportionate impairment on tasks involving feature ambiguity. Experiments 4.1-4.7 investigated the effects of, perirhinal, postrhinal or fornix lesions on aspects of memory for object-context associations. The hypothesis that postrhinal and fornix lesioned animals would be m

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