[Establishment of a bone marrow failure mouse model by immune injury].

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[Establishment of a bone marrow failure mouse model by immune injury].

Lifang Huang,Kun Zhou,Na Zhang,Li Luo,Miao Zheng,Sheng Zhou+2 more-2009-10-01-PubMed

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TL;DRAbstract

The MHC antigen of Balb/c mice is identical to that of DBA/2 mice, but their minor antigen differs. 5.0 Gy irradiation and then 5 x 10(6) lymphocyte infusion can induce BMF similar to the features of aplastic anemia.

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The MHC antigen of Balb/c mice is identical to that of DBA/2 mice, but their minor antigen differs. 5.0 Gy irradiation and then 5 x 10(6) lymphocyte infusion can induce BMF similar to the features of aplastic anemia.

Keywords

PancytopeniaBone marrowAplastic anemiaHaematopoiesisBone marrow failureMedicineSpleenImmune system

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