Prevalence of Haemophilus Influenzae Biotypes and their Clinical Significance

TL;DRAbstract

Background and objectives Haemophilus influenza can lead to several infections in humans. For example it can lead to meningitis, epiglottitis, pneumonia, cellulitis, bacteremia, septic arthritis and conjunctivitis. H. influenza can be classified into seven biotypes independent of their serotypes. Biotypes are determined by three tests including indol production, urease and ornithine decarboxylase. As specific biotypes are associated with different types of infections, sources and antimicrobial resistance patterns, this study was designed to evaluate biotyping in H.influenza and its relationship with the type of infection. Methods In an 18 month period from April 2005 to September 2006, all clinical specimens that were candidate for Haemophilus isolation, were cultured on standard chocolate agar and blood agar with staphylococcal streak technique. Those isolates that showed the phenomenon of satellitism were biotyped by indol production, urease and ornithine decarboxylation tests.Result

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