Impact of dual time point 18-FDG PET/CT in the assessment of pleural effusion in patients with non small cell lung cancer

TL;DRAbstract

1895 Objectives The aim of this study was to assess the utility of dual time point 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) in differentiating benign from malignant pleural disease, in patients with non small cell lung cancer (NSCLC). Methods Sixty-one patients with NSCLC and pleural effusion were included in this retrospective study. All patients had whole body FDG PET/CT imaging at 60+/- 10 min post FDG injection, while 31 patients had second time delayed imaging repeated at 90+/-10 min for the chest. Maximum standardized uptake values (SUVmax) and the average percent change in SUVmax (%SUV) between time point 1and time point 2 were calculated. Malignancy was defined using the following criteria: (1) Visual assessment using three- points grading scale; (2) SUVmax >= 2.4; (3) %SUV >= +9; (4) SUVmax >= 2.4 and/or %SUV >= +9. Anova test and ROC analysis were used in statistical analysis. P value Results Follow up revealed 29 patient with malignant pleural diseas

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