Significance of the detection of paroxysmal nocturnal hemoglobinuria clones in patients with multiple myeloma undergoing autologous stem cell transplantation
Vasileios Chatziantoniou,Stavroula Alexia,Kostas Konstantopoulos,Panagiotis Repousis,Aikaterini Megalakaki,Maria Kotsopoulou+3 more-2015-07-09-Hematology/Oncology and Stem Cell Therapy
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TL;DRAbstract
We confirmed findings of previous reports with current diagnostic guidelines and showed that although the size of the clones may be relatively large, their presence is probably not detrimental. The clinical significance of these clones and the possible mechanisms underlying their expansion in MM must be a subject of further investigation.
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We confirmed findings of previous reports with current diagnostic guidelines and showed that although the size of the clones may be relatively large, their presence is probably not detrimental. The clinical significance of these clones and the possible mechanisms underlying their expansion in MM must be a subject of further investigation.
Keywords
Paroxysmal nocturnal hemoglobinuriaMultiple myelomaMedicineSubclinical infectionCD59HemolysisAutologous stem-cell transplantationClinical significance
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