The Chemotherapy of Infectious Diseases Caused by Protozoa and Bacteria

TL;DRAbstract

The possibility of combating infectious diseases with chemotherapeutically active substances depends to a large extent on the structure of the pathogenic organism. Apart from the cure of contagious pleuro-pneumonia in horses with neosalvarsan, we have, as yet, no chemotherapeutic substance which is active in virus diseases.The position is scarcely better when we turn to bacterial infections due to cocci and bacilli. These two types of infective organisms occupy the lowest level in the scale of micro-organisms. On the other hand, the spirochaetes, which also belong to the bacteria group, and, still more so, those causal organisms belonging to the protozoa, represent relatively highly differentiated species, and the more highly developed a pathogenic organism is, the more points for attack it appears to offer to the action of chemotherapeutic substances.It is, therefore, not to be wondered at that the best results with chemotherapeutically active substances have been obtained in spirocha

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