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Simple qualitative tests for rifampicin in urine

Venkataraman, P,Narayana, A S L,Prabhakar, R-1988-01-01-NIRT Institutional Scholarship Repository (National Institute of Research in Tuberculosis)

TL;DRAbstract

Simple qualitative tests for rifampicin in urine, involving extraction with chloroform
\nas well as with benzene were investigated on 50 patients. A positive test result was obtained in
\n98-100% of the specimens between 3 and 11 hours after drug administration by both methods. All
\nspecimens collected prior to administration of rifampicin as also specimens collected after ingestion
\nof other anti-tuberculosis drugs were negative by both methods. However, the chloroform extraction
\nmethod yielded positive reactions in 26% of 27 specimens collected after the administration of
\nc l o f a z i m i n e .

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Simple qualitative tests for rifampicin in urine, involving extraction with chloroform
\nas well as with benzene were investigated on 50 patients. A positive test result was obtained in
\n98-100% of the specimens between 3 and 11 hours after drug administration by both methods. All
\nspecimens collected prior to administration of rifampicin as also specimens collected after ingestion
\nof other anti-tuberculosis drugs were negative by both methods. However, the chloroform extraction
\nmethod yielded positive reactions in 26% of 27 specimens collected after the administration of
\nc l o f a z i m i n e .

Keywords

RifampicinUrineMedicineTuberculosisClofazimineInternal medicinePathologyLeprosy

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