Guidelines for the control of perinatally transmitted human immunodeficiency virus infection and care of infected mothers, infants and children.

TL;DRAbstract

T he transmission of the human immunodeficiency virus (HIV) from infected mothers to infants, either in utero or perinatally, has been well established.'-10Infection in these infants can be asymptomatic or cause a variety of clinical syndromes including the acquired immunodeficiency syn- drome (AIDS).'It is not, however, conclusively known what proportion of infants exposed in utero or perinatally will be- come infected and in what proportion of infected infants clin- ical disease will develop."2As of December 1, 1985, there were 217 cases of pediatric AIDS reported to the Centers for Disease Control (CDC) (unpublished data).Of these chil- dren, 48% were born to intravenous-drug-using mothers, 17% to Haitians and 10% to mothers who either had AIDS or were sexual partners of men with AIDS or at risk for AIDS.An additional 39 (18 %) children were infected through trans- fusions of infected blood or blood products, and 13 (6 %) had unknown sources of infection.Thus, 165 (76%) of the cases

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