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Open AccessParatext10.1371/journal.pone.0060408.g001

Decreased clonogenic survival of PCa cells exposed to radiation and rucaparib.

Payel Chatterjee,Sachin Gaurav,Arishya Sharma,Singh Kamini,Heston Warren D.,Ciezki Jay+2 more-2015-12-02-Figshare
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TL;DRAbstract

<p><b>A</b>, Radiation and rucaparib dose response in PC3, C4-2, DU145, VCaP and LNCaP cells was established by clonogenic cell survival assays. Left panels indicate the response to radiation, those on the right to rucaparib. <b>B</b>, Synergistic effect of the combination of radiation and rucaparib on clonogenic survival in LNCaP, PC3, C4-2, and VCaP cells, where CI <1 represents synergy and CI >1 an antagonistic interaction between the two treatments. Error bars represent SD of mean (n = 3).</p>

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<p><b>A</b>, Radiation and rucaparib dose response in PC3, C4-2, DU145, VCaP and LNCaP cells was established by clonogenic cell survival assays. Left panels indicate the response to radiation, those on the right to rucaparib. <b>B</b>, Synergistic effect of the combination of radiation and rucaparib on clonogenic survival in LNCaP, PC3, C4-2, and VCaP cells, where CI <1 represents synergy and CI >1 an antagonistic interaction between the two treatments. Error bars represent SD of mean (n = 3).</p>

Keywords

Clonogenic assayCancer researchMedicineBiologyGeneticsApoptosis

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