Connectivity and neuromodulation in the ferret paratracheal ganglion

TL;DRAbstract

Our understanding of connectivity in the ferret paratracheal ganglion, particularly the sites of synapses in motor pathways is in need of further development. Our knowledge of processes modulating neurotransmission, especially the extent of sympathetic neural input to the paratracheal ganglion is also in need of development. Neurotransmission from the vagus to cells in airway ganglia can be blocked by perfusion with norepinephrine. The site(s) where NOR is acting are not known, nor has it been established that there is endogenous norepinephrine which can modulate neurotransmission. We used a suction electrode to record from ganglia associated with the longitudinal nerve trunk (LNT) of the paratracheal ganglion. The LNT was electrically stimulated and evoked potentials were recorded over distances of more than 20 mm. Neurons carrying the signal in the LNT were found to be electrically homogeneous. Perfusing the preparation with low Ca$\\sp{2+}$/high Mg$\\sp{2+}$ Krebs had little or no e

Chat with Paper

AI Agents for this Paper