[External respiratory function, blood oxygenation and the biogenic amine content in different hemodynamic variants of hypertension].

TL;DRAbstract

Pulmonary ventilation and hemodynamics, ventilation/perfusion ratios, arterial blood oxygen and plasma biogenic amines were examined in 126 essentially hypertensive patients with different hemodynamic types. Changes in pulmonary ventilation and hemodynamics result in increased venous admixture in patients with eukinetic hemodynamics, but the arterial blood oxygen level only diminishes in the hypokinetic type. Increased venous admixture is due to a regional decrease in the ventilation/perfusion ratio which is largely dependent on pulmonary hemodynamic disorders. A direct correlation is demonstrated between arterial blood oxygen concentration and daily noradrenaline excretion in eu- and hypokinetic hemodynamic types. Arterial hypoxemia may be responsible for depressed sympathetic activity in patients with these circulation types.

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