Role of iron in infections and immunity

TL;DRAbstract

Maintenance of immune function and defenses against infection requires careful physiological control of various metabolic events. The homeostatic regulation of iron metabolism exemplifies this requirement. The body is faced with the fundamental problem of ensuring that mechanisms exist to allow acquisition of iron by host tissues, while at the same time preventing its becoming readily available to invading microorganisms. For this to occur, two conditions have to be met:

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