Physiological MR imaging techniques and pediatric stroke

TL;DRAbstract

Stroke is an important and under-recognized disorder in children and is one of the top 10 causes of childhood death.[1] Arterial ischemic stroke affects around 8 of 100 000 children annually. Up to a quarter of these children will have a recurrence and two-thirds have long-term disability directly attributable to stroke.[2] Many advances in the understanding of childhood stroke have arisen from the insights available from modern imaging techniques, in particular from MR imaging (MRI). The aims of conventional MRI are not only to detect the infarct but also to provide information to establish the cause of the stroke and to exclude other causes (such as tumor). Clinical applications of physiological MRI techniques (MR diffusion imaging [DWI], MR perfusion imaging, and MR spectroscopy [MRS]) in this group of patients are still largely in the research domain. This chapter will consider arterial ischemic stroke (henceforth abbreviated as stroke) in children over 1 month of age.

Chat with Paper

AI Agents for this Paper