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Up-regulated manganese superoxide dismutase expression increases apoptosis resistance in human esophageal squamous cell carcinomas

Hai Hu,Man‐Li Luo,Xiaoli Du,Yanbin Feng,Yu Zhang,Xiaoming Shen+4 more-2007-12-01-Chinese Medical Journal
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TL;DRAbstract

These findings suggest that there existed two isoforms of MnSOD protein in normal and tumor esophageal tissues. MnSOD was overexpressed in ESCC and its up-regulation in esophageal cancer cells was associated with apoptosis resistance.

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These findings suggest that there existed two isoforms of MnSOD protein in normal and tumor esophageal tissues. MnSOD was overexpressed in ESCC and its up-regulation in esophageal cancer cells was associated with apoptosis resistance.

Keywords

Superoxide dismutaseApoptosisCancer researchManganeseEsophageal squamous cell carcinomaChemistryMedicineInternal medicine

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