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Open AccessBook Chapter10.1007/978-1-59259-229-6_9

Prognostic Factors in Metastatic Renal Cell Carcinoma

Paul Elson-2000-01-01-Humana Press eBooks
26

TL;DRAbstract

It is estimated that almost 30,000 persons were diagnosed with renal cell carcinoma (RCC) in 1998 and that 11,600 deaths were caused by this malignancy (1). If detected early, prior to metastasis, many patients can be cured surgically. The estimated 5-yr survival for patients with disease confined to the kidney (stages T1 and T2) is approximately 90–95% (2). However, once metastatic disease develops, the prognosis for long-term survival is poor, with estimated 5-yr survival of 0–20% (2). Unfortunately, approximately one-third of patients has metastatic disease on initial presentation (2), and therefore, effective treatment strategies for this disease are clearly needed.

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It is estimated that almost 30,000 persons were diagnosed with renal cell carcinoma (RCC) in 1998 and that 11,600 deaths were caused by this malignancy (1). If detected early, prior to metastasis, many patients can be cured surgically. The estimated 5-yr survival for patients with disease confined to the kidney (stages T1 and T2) is approximately 90–95% (2). However, once metastatic disease develops, the prognosis for long-term survival is poor, with estimated 5-yr survival of 0–20% (2). Unfortunately, approximately one-third of patients has metastatic disease on initial presentation (2), and therefore, effective treatment strategies for this disease are clearly needed.

Keywords

Renal cell carcinomaMedicineMalignancyDiseaseMetastasisOncologyInternal medicineCarcinoma

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