The risk factors of toxicity during chemotherapy and radiotherapy in breast cancer patients according to the presence of BRCA gene mutation

doi:https://doi.org/10.5114/wo.2015.50014

Open AccessArticle10.5114/wo.2015.50014

The risk factors of toxicity during chemotherapy and radiotherapy in breast cancer patients according to the presence of BRCA gene mutation

Joanna Huszno,Magdalena Budryk,Zofia Kołosza,Elżbieta Nowara-2015-01-01-Współczesna Onkologia

TL;DRAbstract

Risk factors for anthracycline-based chemotherapy side effects were: age below 70 years, lower WBC value at baseline, history of infectious diseases, hypertension, and cardiovascular comorbidity. The presence of BRCA mutations may be a risk factor for neutropaenia, but it did not affect radiotherapy toxicity.

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Risk factors for anthracycline-based chemotherapy side effects were: age below 70 years, lower WBC value at baseline, history of infectious diseases, hypertension, and cardiovascular comorbidity. The presence of BRCA mutations may be a risk factor for neutropaenia, but it did not affect radiotherapy toxicity.

Keywords

OncologyMedicineRadiation therapyBreast cancerChemotherapyInternal medicineMutationToxicity

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