Age-related variations of enzymatic defenses against free radicals and peroxides

doi:https://doi.org/10.1007/978-3-0348-7460-1_36

Age-related variations of enzymatic defenses against free radicals and peroxides

Yves Artur,Bernard Herbeth,Laı̈la Guemouri,Edith Lecomte,Claude Jeandel,Gérard Siest-1992-01-01-Birkhäuser Basel eBooks

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TL;DRAbstract

Superoxide dismutase, glutathione peroxidase and catalase are the three main enzymatic systems of defense of the organism against free radicals and peroxides. A survey of the literature shows that no general tendency of evolution of these systems in aging emerges, even if some recent studies in humans demonstrate the existence of a concomitant decrease in most of the antioxidant enzymes in blood of the elderly. The study of the antioxidant systems and their interrelations in the elderly represents a large field of future investigations.

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Superoxide dismutase, glutathione peroxidase and catalase are the three main enzymatic systems of defense of the organism against free radicals and peroxides. A survey of the literature shows that no general tendency of evolution of these systems in aging emerges, even if some recent studies in humans demonstrate the existence of a concomitant decrease in most of the antioxidant enzymes in blood of the elderly. The study of the antioxidant systems and their interrelations in the elderly represents a large field of future investigations.

Keywords

CatalaseSuperoxide dismutaseAntioxidantEnzymeGlutathione peroxidaseRadicalPeroxidaseOrganism

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