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Open AccessArticle10.3748/wjg.v12.i7.1037

Loss of heterozygosity of Kras2 gene on 12p12-13 in Chinese colon carcinoma patients

Jun Wan-2006-01-01-World Journal of Gastroenterology
10

TL;DRAbstract

Genomic instability may occur on 12p-12-13 of Kras2 gene in the development and progression of colon carcinoma. The high LOH of Kras2 gene may directly influence the transcription and translation of wild type Kras2 gene.

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Genomic instability may occur on 12p-12-13 of Kras2 gene in the development and progression of colon carcinoma. The high LOH of Kras2 gene may directly influence the transcription and translation of wild type Kras2 gene.

Keywords

Loss of heterozygosityBiologyCarcinomaPathologyMolecular biologyMicrosatellite instabilityPolymerase chain reactionMicrosatellite

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