Intraperitoneale Reduktion der Tumorzelladhäsion mit Phospholipiden : eine tierexperimentelle Studie

TL;DRAbstract

The formation of secondary peritoneal carcinosis is the outcome of intraoperative deportment of tumor cells in the peritoneal cavity. This study deals with the pathomechanism and especially with the adhesion of the colonic tumor cells on the extracellular matrix within the scope of an animal experiment. The positive results in the postoperative prevention of adhesion explain the use of the phospholipids in this study. The formation of adhesions between peritoneum and other tissues or organs predominantly takes place in the lesions of the extracellular matrix. The intraperitoneal application of the phospholipids causes a membranoid protective coating during the wound healing of the lesions. This happens in the case of tumor cell nidation, too. So the intraperitoneal used phospholipids also in this case serve as prevention of adhesion. The study is orientate by the following questions: 1) Is it possible to reduce the adhesion of the tumor cells with intraperitoneal application of phospho

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