Salmonella Brandenburg in New Zealand sheep : the development of a serological diagnostic test and a case control study : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Studies at Massey University

TL;DRAbstract

Salmonella Brandenburg causes acute diarrhoea and severe illness in a variety of animals and was first isolated in New Zealand in 1986. Since 1996 Salmonella Brandenburg has been associated with an emerging epidemic of abortions and deaths in sheep in the southern regions of the South Island. Little is known about the specific epidemiology of Salmonella Brandenburg in sheep and as a result control to date has been largely based on anecdotal evidence and general principles. This study focused on the following aims:
\n• To develop a serological test for use in epidemiological studies and for monitoring future control efforts targeting Salmonella Brandenburg in New Zealand sheep.
\n• To identify factors associated with the occurrence and severity of Salmonella Brandenburg outbreaks in New Zealand sheep.
\nTraditionally Salmonella diagnosis has depended on bacteriological culture. Such tests are time consuming, labour and equipment intensive, and may lack sensitivity. ELISA (En

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