Analysis of Flavonoids and Essential Oils from Clausena Excavata and Their Medicinal Properties

TL;DRAbstract

This study was conducted mainly to determine the major flavonoid compounds and the composition of essential oils predominant in Clausena excavata, and also to examine its antioxidant, antibacterial and anticancer activities. The dried yields of C. excavata’s leaf crude extracts were also determined and methanol was found to be the best solvent for extracting soluble bioactive compounds from the leaves of C. excavata. Total phenolic contents were found abundantly in methanol crude extract of leaves. In the high performance liquid chromatography (HPLC) analysis, rutin and naringin were found predominant in the leaves of C. excavata, while in the gas chromatography-mass spectrometry (GC-MS) analysis, the major chemical components identified in the fruit oil were α-ocimene and terpinolene. Terpinolene was also being the main component and remarkably present in the leaf oil. Both of the fruit and leaf oils extracted with dichloromethane in the simultaneous distillation extraction (SDE) meth

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