Изменение показателей минерального обмена у больных хроническим остеомиелитом
TL;DRAbstract
The authors revealed some regularities of change of mineral metabolism indices in patients with chronic (hematogenic and traumatic) osteomyelitis. The common units of chronic osteomyelitis pathogenesis irrespective of etiology are enlargement of Mg and Cu concentration, increased activity of alkaline phosphatase and decreased level of Ca, CI and Fe in blood serum. Chronic hematogenic osteomyelitis unlike chronic traumatic osteomyelitis is characterized by increased nonorganic phosphates in blood serum and activity of acid phosphatase, and also reduced concentration of Zn. The revealed distinctions in pathogenesis of hematogenic and traumatic osteomyelitis suppose different approach to the treatment. In particular for the treatment of hematogenic osteomyelitis more intensive antiinflammatory and antiresorptive therapy is advisable.
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The authors revealed some regularities of change of mineral metabolism indices in patients with chronic (hematogenic and traumatic) osteomyelitis. The common units of chronic osteomyelitis pathogenesis irrespective of etiology are enlargement of Mg and Cu concentration, increased activity of alkaline phosphatase and decreased level of Ca, CI and Fe in blood serum. Chronic hematogenic osteomyelitis unlike chronic traumatic osteomyelitis is characterized by increased nonorganic phosphates in blood serum and activity of acid phosphatase, and also reduced concentration of Zn. The revealed distinctions in pathogenesis of hematogenic and traumatic osteomyelitis suppose different approach to the treatment. In particular for the treatment of hematogenic osteomyelitis more intensive antiinflammatory and antiresorptive therapy is advisable.
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