RETINAL LESION EVOLUTION IN SUSAC SYNDROME

doi:https://doi.org/10.1097/iae.0000000000000700

RETINAL LESION EVOLUTION IN SUSAC SYNDROME

Alexander U. Brandt,Timm Oberwahrenbrock,Fiona Costello,Michael Fielden,Karen Gertz,Ilka Kleffner+3 more-2015-07-22-Retina

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TL;DRAbstract

The dynamics of lesion development and morphologically distinct lesion sections suggest more complex mechanisms of lesion evolution beyond an isolated endothelial immune reaction and subsequent hypoxic tissue damage. The characteristic lesion morphology assists in differentiating the diagnosis of acute visual loss in neuroinflammatory disease. Specificity of the identified changes has to be determined in future studies also including patients with other retinal vascular diseases.

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The dynamics of lesion development and morphologically distinct lesion sections suggest more complex mechanisms of lesion evolution beyond an isolated endothelial immune reaction and subsequent hypoxic tissue damage. The characteristic lesion morphology assists in differentiating the diagnosis of acute visual loss in neuroinflammatory disease. Specificity of the identified changes has to be determined in future studies also including patients with other retinal vascular diseases.

Keywords

LesionPathologyRetinalRetinaAnatomyNerve fiber layerMedicineOptic nerve

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