TL;DRAbstract
In all diploid organisms such as ourselves, each individual inherits one set of chromosomes from the mother and another set from the father. It is generally assumed that once these chromosomes reach our bodies, they lose any ‘memory’ of where they came from. However there is evidence that chromosomes (and the genes they contain) sometimes get differentially imprinted as they pass through a male or female body and this imprint may be retained when the chromosomes are passed on to the next generation1–6. There is also evidence that DNA methylation is a mechanism by which chromosomes may acquire such male-specific or female- specific imprints.
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In all diploid organisms such as ourselves, each individual inherits one set of chromosomes from the mother and another set from the father. It is generally assumed that once these chromosomes reach our bodies, they lose any ‘memory’ of where they came from. However there is evidence that chromosomes (and the genes they contain) sometimes get differentially imprinted as they pass through a male or female body and this imprint may be retained when the chromosomes are passed on to the next generation1–6. There is also evidence that DNA methylation is a mechanism by which chromosomes may acquire such male-specific or female- specific imprints.
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