Research Topic

Hypertrophic osteoarthropathy and related conditions

This cluster of papers focuses on primary hypertrophic osteoarthropathy and related conditions such as pachydermoperiostosis, digital clubbing, and small intestinal ulceration. It explores the genetic mutations, pathophysiology, clinical features, and treatment options for these conditions, with a particular emphasis on the role of prostaglandin transporter gene SLCO2A1 and vascular endothelial growth factor.