Research Topic

Polyomavirus and related diseases

This cluster of papers focuses on the association between polyomaviruses, particularly Merkel cell polyomavirus and JC virus, with the development of malignancies such as Merkel cell carcinoma and the manifestation of progressive multifocal leukoencephalopathy in immunocompromised individuals. It also explores the impact of immunosuppressive therapies, viral replication in renal transplant recipients, and the potential role of viral oncoproteins in promoting tumorigenesis.