Research Topic

Systemic Sclerosis and Related Diseases

This cluster of papers focuses on the pathogenesis, clinical manifestations, and treatment of systemic sclerosis, with an emphasis on fibrosis, autoantibodies, pulmonary involvement, and the role of TGF-ß signaling. It also explores genetic markers, endothelial dysfunction, and various treatment approaches including immunosuppressive therapy for this complex autoimmune disease.