Research Topic

Advanced Glycation End Products research

This cluster of papers focuses on the biochemistry and molecular cell biology of diabetic complications, particularly exploring the role of Advanced Glycation End Products (AGEs), HMGB1, oxidative stress, inflammation, and the receptor for AGEs (RAGE) in the pathobiology of diabetes. The papers also delve into the involvement of mitochondrial superoxide, toll-like receptors, necrotic cells, and cellular signaling pathways in diabetic complications.