Research Topic

Ubiquitin and proteasome pathways

This cluster of papers focuses on the Ubiquitin-Proteasome Proteolytic Pathway, exploring mechanisms of protein degradation, regulation of E3 Ubiquitin Ligases, roles of Deubiquitinating Enzymes, and the impact of SUMOylation. It also delves into the development of proteasome inhibitors for cancer therapy and the involvement of this pathway in NF-?B activation.